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Add TCGA Pancan pathways to query selector #4610

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merged 3 commits into from
May 11, 2023
Merged

Add TCGA Pancan pathways to query selector #4610

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8cf3e74
Add TCGA Pancan pathways to query selector
inodb May 2, 2023
da7159a
fix indent
inodb May 2, 2023
ee3dead
fix json pathway typo
inodb May 2, 2023
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211 changes: 211 additions & 0 deletions src/shared/components/query/gene_lists.ts
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Original file line number Diff line number Diff line change
Expand Up @@ -163,6 +163,217 @@ const gene_lists = [
'PEG3',
],
},
{
id: 'General: Cell Cycle - TCGA PanCan Pathways',
genes: [
'CDKN1A',
'CDKN1B',
'CDKN2A',
'CDKN2B',
'CDKN2C',
'CCND1',
'CCND2',
'CCND3',
'CCNE1',
'CDK2',
'CDK4',
'CDK6',
'RB1',
'E2F1',
'E2F3',
],
},
{
id: 'General: HIPPO - TCGA PanCan Pathways',
genes: [
'STK4',
'STK3',
'SAV1',
'LATS1',
'LATS2',
'MOB1A',
'MOB1B',
'YAP1',
'TEAD2',
'PTPN14',
'NF2',
'WWC1',
'TAOK1',
'TAOK2',
'TAOK3',
'CRB1',
'CRB2',
'CRB3',
'FAT1',
'FAT2',
'FAT3',
'FAT4',
'DCHS1',
'DCHS2',
'CSNK1E',
'CSNK1D',
],
},
{
id: 'General: MYC - TCGA PanCan Pathways',
genes: ['MAX', 'MGA', 'MLX', 'MNT', 'MXI1', 'MYC', 'MYCN'],
},
{
id: 'General: NOTCH - TCGA PanCan Pathways',
genes: [
'ARRDC1',
'CNTN6',
'CREBBP',
'EP300',
'HES1',
'HES2',
'HES3',
'HES4',
'HES5',
'HEY1',
'HEY2',
'HEYL',
'KAT2B',
'KDM5A',
'NOTCH1',
'NOTCH2',
'NOTCH3',
'NOTCH4',
'NOV',
'PSEN2',
'SPEN',
'FBXW7',
'THBS2',
'CUL1',
'NCOR1',
'NCOR2',
'HDAC1',
'JAG2',
'MAML3',
'DNER',
],
},
{
id: 'General: NRF2 - TCGA PanCan Pathways',
genes: ['NFE2L2', 'KEAP1', 'CUL3'],
},
{
id: 'General: PI3K - TCGA PanCan Pathways',
genes: [
'AKT1',
'AKT2',
'AKT3',
'INPP4B',
'MLST8',
'MTOR',
'NPRL2',
'NPRL3',
'PIK3CA',
'PIK3CB',
'PIK3R1',
'PIK3R2',
'PIK3R3',
'PPP2R1A',
'PTEN',
'RHEB',
'RICTOR',
'RPTOR',
'RPS6KB1',
'STK11',
'TSC1',
'TSC2',
],
},
{
id: 'General: TGF-Beta - TCGA PanCan Pathways',
genes: [
'TGFBR1',
'TGFBR2',
'ACVR2A',
'ACVR1B',
'SMAD2',
'SMAD3',
'SMAD4',
],
},
{
id: 'General: RTK-RAS - TCGA PanCan Pathways',
genes: [
'ABL1',
'EGFR',
'ERBB2',
'ERBB3',
'ERBB4',
'PDGFRA',
'MET',
'FGFR1',
'FGFR2',
'FGFR3',
'FGFR4',
'FLT3',
'ALK',
'RET',
'ROS1',
'KIT',
'IGF1R',
'NTRK1',
'NTRK2',
'NTRK3',
'SOS1',
'GRB2',
'PTPN11',
'KRAS',
'HRAS',
'NRAS',
'RIT1',
'ARAF',
'BRAF',
'RAF1',
'RAC1',
'MAP2K1',
'MAP2K2',
'MAPK1',
'NF1',
'RASA1',
'CBL',
'ERRFI1',
'JAK2',
],
},
{
id: 'General: TP53 - TCGA PanCan Pathways',
genes: ['TP53', 'MDM2', 'MDM4', 'ATM', 'CHEK2', 'RPS6KA3'],
},
{
id: 'General: WNT - TCGA PanCan Pathways',
genes: [
'SFRP1',
'SFRP2',
'SFRP4',
'SFRP5',
'SOST',
'TCF7L1',
'TLE1',
'TLE2',
'TLE3',
'TLE4',
'WIF1',
'ZNRF3',
'CTNNB1',
'AMER1',
'APC',
'AXIN1',
'AXIN2',
'DKK1',
'DKK2',
'DKK3',
'DKK4',
'GSK3B',
'RNF43',
'TCF7',
'TCF7L2',
],
},
{
id: 'General: Cell Cycle Control',
genes: [
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