diff --git a/src/libraries/Native/Unix/System.Globalization.Native/pal_collation.c b/src/libraries/Native/Unix/System.Globalization.Native/pal_collation.c
index 4a4c969485cb1c..f0273afac9fa6c 100644
--- a/src/libraries/Native/Unix/System.Globalization.Native/pal_collation.c
+++ b/src/libraries/Native/Unix/System.Globalization.Native/pal_collation.c
@@ -365,6 +365,25 @@ static UCollator* CloneCollatorWithOptions(const UCollator* pCollator, int32_t o
     {
         ucol_setAttribute(pClonedCollator, UCOL_ALTERNATE_HANDLING, UCOL_SHIFTED, pErr);
 
+#if !defined(STATIC_ICU)
+    if (ucol_setMaxVariable_ptr != NULL)
+    {
+        // by default, ICU alternate shifted handling only ignores punctuation, but
+        // IgnoreSymbols needs symbols and currency as well, so change the "variable top"
+        // to include all symbols and currency
+        ucol_setMaxVariable(pClonedCollator, UCOL_REORDER_CODE_CURRENCY, pErr);
+    }
+    else
+    {
+        assert(ucol_setVariableTop_ptr != NULL);
+        // 0xfdfc is the last currency character before the first digit character
+        // in http://source.icu-project.org/repos/icu/icu/tags/release-52-1/source/data/unidata/FractionalUCA.txt
+        const UChar ignoreSymbolsVariableTop[] = { 0xfdfc };
+        ucol_setVariableTop_ptr(pClonedCollator, ignoreSymbolsVariableTop, 1, pErr);
+    }
+
+#else // !defined(STATIC_ICU)
+
         // by default, ICU alternate shifted handling only ignores punctuation, but
         // IgnoreSymbols needs symbols and currency as well, so change the "variable top"
         // to include all symbols and currency
@@ -376,6 +395,8 @@ static UCollator* CloneCollatorWithOptions(const UCollator* pCollator, int32_t o
         const UChar ignoreSymbolsVariableTop[] = { 0xfdfc };
         ucol_setVariableTop(pClonedCollator, ignoreSymbolsVariableTop, 1, pErr);
 #endif
+
+#endif //!defined(STATIC_ICU)
     }
 
     ucol_setAttribute(pClonedCollator, UCOL_STRENGTH, strength, pErr);
diff --git a/src/libraries/Native/Unix/System.Globalization.Native/pal_icushim.c b/src/libraries/Native/Unix/System.Globalization.Native/pal_icushim.c
index 4f71b66c2678f8..70e8f0944993d2 100644
--- a/src/libraries/Native/Unix/System.Globalization.Native/pal_icushim.c
+++ b/src/libraries/Native/Unix/System.Globalization.Native/pal_icushim.c
@@ -38,6 +38,7 @@ FOR_ALL_ICU_FUNCTIONS
 
 static void* libicuuc = NULL;
 static void* libicui18n = NULL;
+ucol_setVariableTop_func ucol_setVariableTop_ptr = NULL;
 
 #if defined (TARGET_UNIX)
 
@@ -380,6 +381,34 @@ static void ValidateICUDataCanLoad()
     }
 }
 
+static void InitializeVariableMaxAndTopPointers(char* symbolVersion)
+{
+    if (ucol_setMaxVariable_ptr != NULL)
+    {
+        return;
+    }
+
+#if defined(TARGET_OSX) || defined(TARGET_ANDROID)
+    // OSX and Android always run against ICU version which has ucol_setMaxVariable.
+    // We shouldn't come here.
+    assert(false);
+#elif defined(TARGET_WINDOWS)
+    char symbolName[SYMBOL_NAME_SIZE];
+    sprintf_s(symbolName, SYMBOL_NAME_SIZE, "ucol_setVariableTop%s", symbolVersion);
+    ucol_setVariableTop_ptr = (ucol_setVariableTop_func)GetProcAddress((HMODULE)libicui18n, symbolName);
+#else
+    char symbolName[SYMBOL_NAME_SIZE];
+    sprintf(symbolName, "ucol_setVariableTop%s", symbolVersion);
+    ucol_setVariableTop_ptr = (ucol_setVariableTop_func)dlsym(libicui18n, symbolName);
+#endif // defined(TARGET_OSX) || defined(TARGET_ANDROID)
+
+    if (ucol_setVariableTop_ptr == NULL)
+    {
+        fprintf(stderr, "Cannot get the symbols of ICU APIs ucol_setMaxVariable or ucol_setVariableTop.\n");
+        abort();
+    }
+}
+
 // GlobalizationNative_LoadICU
 // This method get called from the managed side during the globalization initialization.
 // This method shouldn't get called at all if we are running in globalization invariant mode
@@ -413,6 +442,9 @@ int32_t GlobalizationNative_LoadICU()
 
     FOR_ALL_ICU_FUNCTIONS
     ValidateICUDataCanLoad();
+
+    InitializeVariableMaxAndTopPointers(symbolVersion);
+
     return true;
 }
 
@@ -466,6 +498,8 @@ void GlobalizationNative_InitICUFunctions(void* icuuc, void* icuin, const char*
 
     FOR_ALL_ICU_FUNCTIONS
     ValidateICUDataCanLoad();
+
+    InitializeVariableMaxAndTopPointers(symbolVersion);
 }
 
 #undef PER_FUNCTION_BLOCK
diff --git a/src/libraries/Native/Unix/System.Globalization.Native/pal_icushim_internal.h b/src/libraries/Native/Unix/System.Globalization.Native/pal_icushim_internal.h
index 1ddaff5594aad3..e752c7d006d5fd 100644
--- a/src/libraries/Native/Unix/System.Globalization.Native/pal_icushim_internal.h
+++ b/src/libraries/Native/Unix/System.Globalization.Native/pal_icushim_internal.h
@@ -53,11 +53,17 @@
 #include "pal_compiler.h"
 
 #if !defined(STATIC_ICU)
+// ucol_setVariableTop is a deprecated function on the newer ICU versions and ucol_setMaxVariable should be used instead.
+// As can run against ICU versions which not supported ucol_setMaxVariable, we'll dynamically try to get the pointer to ucol_setVariableTop
+// when we couldn't get a pointer to ucol_setMaxVariable.
+typedef uint32_t (*ucol_setVariableTop_func)(UCollator* coll, const UChar* varTop, int32_t len, UErrorCode* status);
+extern ucol_setVariableTop_func ucol_setVariableTop_ptr;
 
 #if !defined(TARGET_ANDROID)
 // (U_ICU_VERSION_MAJOR_NUM < 52)
 // The following APIs are not supported in the ICU versions less than 52. We need to define them manually.
 // We have to do runtime check before using the pointers to these APIs. That is why these are listed in the FOR_ALL_OPTIONAL_ICU_FUNCTIONS list.
+U_CAPI void U_EXPORT2 ucol_setMaxVariable(UCollator* coll, UColReorderCode group, UErrorCode* pErrorCode);
 U_CAPI int32_t U_EXPORT2 ucal_getTimeZoneIDForWindowsID(const UChar* winid, int32_t len, const char* region, UChar* id, int32_t idCapacity, UErrorCode* status);
 U_CAPI int32_t U_EXPORT2 ucal_getWindowsTimeZoneID(const UChar* id, int32_t len, UChar* winid, int32_t winidCapacity, UErrorCode* status);
 #endif
@@ -164,15 +170,6 @@ U_CAPI int32_t U_EXPORT2 ucal_getWindowsTimeZoneID(const UChar* id, int32_t len,
     PER_FUNCTION_BLOCK(usearch_setPattern, libicui18n, true) \
     PER_FUNCTION_BLOCK(usearch_setText, libicui18n, true)
 
-#if HAVE_SET_MAX_VARIABLE
-#define FOR_ALL_SET_VARIABLE_ICU_FUNCTIONS \
-    PER_FUNCTION_BLOCK(ucol_setMaxVariable, libicui18n, true)
-#else
-
-#define FOR_ALL_SET_VARIABLE_ICU_FUNCTIONS \
-    PER_FUNCTION_BLOCK(ucol_setVariableTop, libicui18n, true)
-#endif
-
 #if defined(TARGET_WINDOWS)
 #define FOR_ALL_OS_CONDITIONAL_ICU_FUNCTIONS \
     PER_FUNCTION_BLOCK(ucurr_forLocale, libicuuc, true) \
@@ -195,11 +192,11 @@ U_CAPI int32_t U_EXPORT2 ucal_getWindowsTimeZoneID(const UChar* id, int32_t len,
 // Otherwise, we'll just not provide the functionality to users which needed these APIs.
 #define FOR_ALL_OPTIONAL_ICU_FUNCTIONS \
     PER_FUNCTION_BLOCK(ucal_getWindowsTimeZoneID, libicui18n, false) \
-    PER_FUNCTION_BLOCK(ucal_getTimeZoneIDForWindowsID, libicui18n, false)
+    PER_FUNCTION_BLOCK(ucal_getTimeZoneIDForWindowsID, libicui18n, false) \
+    PER_FUNCTION_BLOCK(ucol_setMaxVariable, libicui18n, false)
 
 #define FOR_ALL_ICU_FUNCTIONS \
     FOR_ALL_UNCONDITIONAL_ICU_FUNCTIONS \
-    FOR_ALL_SET_VARIABLE_ICU_FUNCTIONS \
     FOR_ALL_OPTIONAL_ICU_FUNCTIONS \
     FOR_ALL_OS_CONDITIONAL_ICU_FUNCTIONS
 
@@ -249,11 +246,7 @@ FOR_ALL_ICU_FUNCTIONS
 #define ucol_openRules(...) ucol_openRules_ptr(__VA_ARGS__)
 #define ucol_safeClone(...) ucol_safeClone_ptr(__VA_ARGS__)
 #define ucol_setAttribute(...) ucol_setAttribute_ptr(__VA_ARGS__)
-#if HAVE_SET_MAX_VARIABLE
 #define ucol_setMaxVariable(...) ucol_setMaxVariable_ptr(__VA_ARGS__)
-#else
-#define ucol_setVariableTop(...) ucol_setVariableTop_ptr(__VA_ARGS__)
-#endif
 #define ucol_strcoll(...) ucol_strcoll_ptr(__VA_ARGS__)
 #define ucurr_forLocale(...) ucurr_forLocale_ptr(__VA_ARGS__)
 #define ucurr_getName(...) ucurr_getName_ptr(__VA_ARGS__)