-
Notifications
You must be signed in to change notification settings - Fork 2
/
Copy pathsbo.owl
10400 lines (10377 loc) · 472 KB
/
sbo.owl
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
438
439
440
441
442
443
444
445
446
447
448
449
450
451
452
453
454
455
456
457
458
459
460
461
462
463
464
465
466
467
468
469
470
471
472
473
474
475
476
477
478
479
480
481
482
483
484
485
486
487
488
489
490
491
492
493
494
495
496
497
498
499
500
501
502
503
504
505
506
507
508
509
510
511
512
513
514
515
516
517
518
519
520
521
522
523
524
525
526
527
528
529
530
531
532
533
534
535
536
537
538
539
540
541
542
543
544
545
546
547
548
549
550
551
552
553
554
555
556
557
558
559
560
561
562
563
564
565
566
567
568
569
570
571
572
573
574
575
576
577
578
579
580
581
582
583
584
585
586
587
588
589
590
591
592
593
594
595
596
597
598
599
600
601
602
603
604
605
606
607
608
609
610
611
612
613
614
615
616
617
618
619
620
621
622
623
624
625
626
627
628
629
630
631
632
633
634
635
636
637
638
639
640
641
642
643
644
645
646
647
648
649
650
651
652
653
654
655
656
657
658
659
660
661
662
663
664
665
666
667
668
669
670
671
672
673
674
675
676
677
678
679
680
681
682
683
684
685
686
687
688
689
690
691
692
693
694
695
696
697
698
699
700
701
702
703
704
705
706
707
708
709
710
711
712
713
714
715
716
717
718
719
720
721
722
723
724
725
726
727
728
729
730
731
732
733
734
735
736
737
738
739
740
741
742
743
744
745
746
747
748
749
750
751
752
753
754
755
756
757
758
759
760
761
762
763
764
765
766
767
768
769
770
771
772
773
774
775
776
777
778
779
780
781
782
783
784
785
786
787
788
789
790
791
792
793
794
795
796
797
798
799
800
801
802
803
804
805
806
807
808
809
810
811
812
813
814
815
816
817
818
819
820
821
822
823
824
825
826
827
828
829
830
831
832
833
834
835
836
837
838
839
840
841
842
843
844
845
846
847
848
849
850
851
852
853
854
855
856
857
858
859
860
861
862
863
864
865
866
867
868
869
870
871
872
873
874
875
876
877
878
879
880
881
882
883
884
885
886
887
888
889
890
891
892
893
894
895
896
897
898
899
900
901
902
903
904
905
906
907
908
909
910
911
912
913
914
915
916
917
918
919
920
921
922
923
924
925
926
927
928
929
930
931
932
933
934
935
936
937
938
939
940
941
942
943
944
945
946
947
948
949
950
951
952
953
954
955
956
957
958
959
960
961
962
963
964
965
966
967
968
969
970
971
972
973
974
975
976
977
978
979
980
981
982
983
984
985
986
987
988
989
990
991
992
993
994
995
996
997
998
999
1000
<rdf:RDF
xmlns="http://biomodels.net/SBO/"
xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
xmlns:owl="http://www.w3.org/2002/07/owl#"
xmlns:mathml="http://www.w3.org/1998/Math/MathML"
xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
xmlns:daml="http://www.daml.org/2001/03/daml+oil#"
xml:base="http://biomodels.net/SBO/">
<owl:Ontology rdf:about="">
<rdfs:comment xml:lang="EN">Systems Biology Ontology, OWL export generated by SBO Browser (http://www.ebi.ac.uk/sbo/)</rdfs:comment>
<owl:versionInfo>13:07:2018 10:45</owl:versionInfo>
<rdfs:label xml:lang="EN">Generated: 04:04:2019 07:00</rdfs:label>
</owl:Ontology>
<owl:Class rdf:about="SBO_0000588">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000185"/>
</rdfs:subClassOf>
<rdfs:comment>A transport reaction which results in the removal of the transported entity from the cell.</rdfs:comment>
<rdfs:label>transcellular membrane efflux reaction</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000661">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000002"/>
</rdfs:subClassOf>
<rdfs:comment>Total amount that can be contained or produced by a specific entity. This can refer to diverse items, such as the carrying capacity of a membrane with respect to proteins, the capacity of high-energy phosphate bonds, or the maximal count of bacteria in the gut, etc.</rdfs:comment>
<rdfs:label>capacity</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000540">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000360"/>
</rdfs:subClassOf>
<rdfs:comment>A ratio that represents the quantity of a defined constituent entity over the total number of all constituent entities present. </rdfs:comment>
<rdfs:label>fraction of an entity pool</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000310">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000309"/>
</rdfs:subClassOf>
<rdfs:comment>Quantitative parameter that characterises an acid-base reaction.</rdfs:comment>
<rdfs:label>acid dissociation characteristic</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000431">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000425"/>
</rdfs:subClassOf>
<rdfs:seeAlso rdf:parseType="Literal"> <mathml:math>
<semantics definitionURL="http://biomodels.net/SBO/#SBO:0000062">
<lambda>
<bvar>
<ci definitionURL="http://biomodels.net/SBO/#SBO:0000515"> substrate
</ci>
</bvar>
<bvar>
<ci definitionURL="http://biomodels.net/SBO/#SBO:0000512"> product
</ci>
</bvar>
<bvar>
<ci definitionURL="http://biomodels.net/SBO/#SBO:0000281"> Keq
</ci>
</bvar>
<bvar>
<ci definitionURL="http://biomodels.net/SBO/#SBO:0000324"> Vf
</ci>
</bvar>
<bvar>
<ci definitionURL="http://biomodels.net/SBO/#SBO:0000424"> Ks
</ci>
</bvar>
<bvar>
<ci definitionURL="http://biomodels.net/SBO/#SBO:0000423"> Kp
</ci>
</bvar>
<bvar>
<ci definitionURL="http://biomodels.net/SBO/#SBO:0000190"> h
</ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci> Vf </ci>
<ci> substrate </ci>
</apply>
<ci> Ks</ci>
</apply>
<apply>
<minus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> product </ci>
<apply>
<times/>
<ci> substrate </ci>
<ci> Keq </ci>
</apply>
</apply>
</apply>
<apply>
<power/>
<apply>
<plus/>
<apply>
<divide/>
<ci> substrate </ci>
<ci> Ks</ci>
</apply>
<apply>
<divide/>
<ci> product </ci>
<ci> Kp </ci>
</apply>
</apply>
<apply>
<minus/>
<ci> h </ci>
<cn> 1 </cn>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<power/>
<apply>
<plus/>
<apply>
<divide/>
<ci> substrate </ci>
<ci> Ks</ci>
</apply>
<apply>
<divide/>
<ci> product </ci>
<ci> Kp </ci>
</apply>
</apply>
<ci> h </ci>
</apply>
</apply>
</apply>
</lambda>
</semantics>
</mathml:math></rdfs:seeAlso>
<rdfs:comment>Reversible equivalent of Hill kinetics, where substrate and product bind co-operatively to the enzyme. A Hill coefficient (h) of greater than 1 indicates positive co-operativity between substrate and product, while h values below 1 indicate negative co-operativity.
</rdfs:comment>
<rdfs:label>unmodulated reversible Hill-type rate law</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000552">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000550"/>
</rdfs:subClassOf>
<rdfs:comment>Additional information that supplements existing data, usually in a document, by providing a link to more detailed information, which is held externally, or elsewhere.</rdfs:comment>
<rdfs:label>reference annotation</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000443">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000430"/>
</rdfs:subClassOf>
<rdfs:comment>Synonym: specific activation </rdfs:comment>
<rdfs:label>enzymatic rate law for reversible essential activation</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000564">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000562"/>
</rdfs:subClassOf>
<rdfs:seeAlso rdf:parseType="Literal"><mathml:math>
<semantics definitionURL="http://biomodels.net/SBO/#SBO:0000063">
<lambda>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000067">c</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000508">R</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000523">A</ci></bvar>
<apply>
<times/>
<ci>c</ci>
<ci>R</ci>
<ci>A</ci>
</apply>
</lambda>
</semantics>
</mathml:math></rdfs:seeAlso>
<rdfs:comment>Reaction scheme where the products are created from a reactant and the change of a product quantity is proportional to the product of the reactant and the stimulator quantities. The reaction scheme does not include any reverse process that creates the reactant from the products. The change of a product quantity is proportional to the quantity of the reactant and the stimulator. It is to be used in a reaction modelled using a discrete framework.</rdfs:comment>
<rdfs:label>mass action like rate law for second order irreversible reactions, one reactant, one essential stimulator, discrete scheme</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000213">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000211"/>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000208"/>
</rdfs:subClassOf>
<rdfs:comment>Removal of a proton (hydrogen ion H+) from a chemical entity.</rdfs:comment>
<rdfs:label>deprotonation</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000322">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000027"/>
</rdfs:subClassOf>
<rdfs:comment>Synonym: Kms </rdfs:comment>
<rdfs:label>Michaelis constant for substrate</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000334">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000404"/>
</rdfs:subClassOf>
<rdfs:comment>RNA molecule that is not translated into a protein.
Sequence Ontology SO:0000655</rdfs:comment>
<rdfs:label>non-coding RNA</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000455">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000454"/>
</rdfs:subClassOf>
<rdfs:seeAlso rdf:parseType="Literal"> <mathml:math>
<semantics definitionURL="http://biomodels.net/SBO/#SBO:0000062">
<lambda>
<bvar>
<ci definitionURL="http://biomodels.net/SBO/#SBO:0000515"> substrate </ci>
</bvar>
<bvar>
<ci definitionURL="http://biomodels.net/SBO/#SBO:0000027"> Km </ci>
</bvar>
<bvar>
<ci definitionURL="http://biomodels.net/SBO/#SBO:0000324"> V </ci>
</bvar>
<bvar>
<ci definitionURL="http://biomodels.net/SBO/#SBO:0000261"> Ki </ci>
</bvar>
<apply>
<divide/>
<apply>
<times/>
<ci> V </ci>
<ci> substrate </ci>
</apply>
<apply>
<plus/>
<ci> Km </ci>
<ci> substrate </ci>
<apply>
<times/>
<ci> Km </ci>
<apply>
<power/>
<apply>
<divide/>
<ci> substrate </ci>
<ci> Ki </ci>
</apply>
<cn> 2 </cn>
</apply>
</apply>
</apply>
</apply>
</lambda>
</semantics>
</mathml:math></rdfs:seeAlso>
<rdfs:comment>Enzymatic rate law where the substrate for an enzyme also acts as an irreversible inhibitor. This may entail a second (non-active) binding site for the enzyme. The inhibition constant is then the dissociation constant for the substrate from this second site.
</rdfs:comment>
<rdfs:label>enzymatic rate law for irreversible substrate inhibition</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000201">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000200"/>
</rdfs:subClassOf>
<rdfs:comment>Chemical process during which a molecular entity loses electrons.</rdfs:comment>
<rdfs:label>oxidation</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000576">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000571"/>
</rdfs:subClassOf>
<rdfs:comment>A thermodynamic property which acts as a measure of the state of disorder
of a system. Its natural variables are the internal energy (U) and the
volume (V). It is defined by dS = (1/T)dU + (p/T)dV. The second law of
thermodynamics states that in an isolated system, natural processes tend
to increase in disorder or entropy. The standard unit of measure is Joules
per Kelvin (J/K).
symbol: S</rdfs:comment>
<rdfs:label>entropy</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000346">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000002"/>
</rdfs:subClassOf>
<rdfs:comment>Fundamental quantity of the measuring system used to sequence events, to compare the durations of events and the intervals between them, and to quantify the motions or the transformation of entities. The SI base unit for time is the SI second. The second is the duration of 9,192,631,770 periods of the radiation corresponding to the transition between the two hyperfine levels of the ground state of the caesium 133 atom.</rdfs:comment>
<rdfs:label>temporal measure</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000467">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000465"/>
</rdfs:subClassOf>
<rdfs:comment>The area of an object is a quantity expressing its two-dimensional size, usually part or all of its surface. </rdfs:comment>
<rdfs:label>area</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000116">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000110"/>
</rdfs:subClassOf>
<rdfs:comment>Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant and the square of quantity of the other reactant. The rate of the reverse process is proportional to the quantity of three products.</rdfs:comment>
<rdfs:label>mass action rate law for third order forward, third order reverse, reversible reactions, two reactants</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000237">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000374"/>
</rdfs:subClassOf>
<rdfs:comment>Combining the influence of several entities or events in a unique influence.</rdfs:comment>
<rdfs:label>logical combination</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000358">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000375"/>
</rdfs:subClassOf>
<rdfs:comment>A biochemical network can generate phenotypes or affects biological processes. Such processes can take place at different levels and are independent of the biochemical network itself.
</rdfs:comment>
<rdfs:label>phenotype</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000104">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000102"/>
</rdfs:subClassOf>
<rdfs:seeAlso rdf:parseType="Literal"><mathml:math>
<semantics definitionURL="http://biomodels.net/SBO/#SBO:0000062">
<lambda>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000036">kf</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000039">kr</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000509">R1</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000509">R2</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000512">P1</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000512">P2</ci></bvar>
<apply>
<minus/>
<apply>
<times/>
<ci>kf</ci>
<ci>R1</ci>
<ci>R2</ci>
</apply>
<apply>
<times/>
<ci>kr</ci>
<ci>P1</ci>
<ci>P2</ci>
</apply>
</apply>
</lambda>
</semantics>
</mathml:math></rdfs:seeAlso>
<rdfs:comment>Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of two reactant quantities. The rate of the reverse process is proportional to the product of two product quantities. It is to be used in a reaction modelled using a continuous framework.</rdfs:comment>
<rdfs:label>mass action rate law for second order forward, second order reverse, reversible reactions, two reactants, two products, continuous scheme</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000479">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000478"/>
</rdfs:subClassOf>
<rdfs:seeAlso rdf:parseType="Literal"><mathml:math>
<lambda>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000322">Kms</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000149">x</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000481">n</ci></bvar>
<apply>
<product/>
<bvar><ci> i </ci></bvar>
<lowlimit><cn type="integer"> 1 </cn></lowlimit>
<uplimit><ci> x </ci></uplimit>
<apply>
<power/>
<apply>
<selector/>
<ci type="vector">Kms</ci>
<ci> i </ci>
</apply>
<apply>
<selector/>
<ci type="vector">n</ci>
<ci> i </ci>
</apply>
</apply>
</apply>
</lambda>
</mathml:math>
</rdfs:seeAlso>
<rdfs:comment>The product of the substrate Michaelis constants, to the power of their respective stoichiometric coefficients.</rdfs:comment>
<rdfs:label>powered product of substrate Michaelis constants</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000225">
<rdfs:subClassOf rdf:resource="SBO_0000346"/>
<rdfs:comment>Time during which some action is awaited.</rdfs:comment>
<rdfs:label>delay</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000249">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000248"/>
</rdfs:subClassOf>
<rdfs:comment>Macromolecule consisting of a large number of monosaccharide residues linked by glycosidic bonds.
CHEBI:18154</rdfs:comment>
<rdfs:label>polysaccharide</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000128">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000126"/>
</rdfs:subClassOf>
<rdfs:seeAlso rdf:parseType="Literal"><mathml:math>
<semantics definitionURL="http://biomodels.net/SBO/#SBO:0000062">
<lambda>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000037">kf</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000040">kr</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000509">R1</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000509">R2</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000509">R3</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000512">P1</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000512">P2</ci></bvar>
<apply>
<minus/>
<apply>
<times/>
<ci>kf</ci>
<ci>R1</ci>
<ci>R2</ci>
<ci>R3</ci>
</apply>
<apply>
<times/>
<ci>kr</ci>
<ci>P1</ci>
<ci>P1</ci>
<ci>P2</ci>
</apply>
</apply>
</lambda>
</semantics>
</mathml:math></rdfs:seeAlso>
<rdfs:comment>Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of three reactant quantities. The rate of the reverse process is proportional to the quantity of one product and the square of the quantity of the other product. It is to be used in a reaction modelled using a continuous framework.</rdfs:comment>
<rdfs:label>mass action rate law for third order forward, third order reverse, reversible reactions, three reactants, two products, continuous scheme</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000007">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000235"/>
</rdfs:subClassOf>
<rdfs:comment>The 'kind' of entity involved in some process, action or reaction in the system. This may be enzyme, simple chemical, etc..</rdfs:comment>
<rdfs:label>obsolete participant type</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000019">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000003"/>
</rdfs:subClassOf>
<rdfs:comment>Substance that changes the velocity of a process without
itself being consumed or transformed by the reaction.</rdfs:comment>
<rdfs:label>modifier</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000599">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000473"/>
</rdfs:subClassOf>
<rdfs:comment>A denotement that specifies a point of contact between variables or submodels in a hierarchical model.</rdfs:comment>
<rdfs:label>port</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000587">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000185"/>
</rdfs:subClassOf>
<rdfs:comment>A transport reaction which results in the entry of the transported entity, into the cell.</rdfs:comment>
<rdfs:label>transcellular membrane influx reaction</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000660">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000654"/>
</rdfs:subClassOf>
<rdfs:comment>A membrane protein mediated transport of two or more molecules in opposite directions across a membrane.</rdfs:comment>
<rdfs:label>antiporter-mediated transport</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000430">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000269"/>
</rdfs:subClassOf>
<rdfs:comment>Kinetics of enzymes that react with one substance, and whose activity may be positively or negatively modulated.</rdfs:comment>
<rdfs:label>enzymatic rate law for modulated unireactant enzymes</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000551">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000555"/>
</rdfs:subClassOf>
<rdfs:comment>The use of an abbreviated name, taken from a controlled vocabulary of terms, which is used to represent some information about the entity to which it is attached.</rdfs:comment>
<rdfs:label>controlled short label</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000200">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000176"/>
</rdfs:subClassOf>
<rdfs:comment>Chemical process in which atoms have their oxidation number (oxidation state) changed.</rdfs:comment>
<rdfs:label>redox reaction</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000442">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000265"/>
</rdfs:subClassOf>
<rdfs:seeAlso rdf:parseType="Literal"> <mathml:math>
<semantics definitionURL="http://biomodels.net/SBO/#SBO:0000062">
<lambda>
<bvar>
<ci definitionURL="http://biomodels.net/SBO/#SBO:0000515"> substrate </ci>
</bvar>
<bvar>
<ci definitionURL="http://biomodels.net/SBO/#SBO:0000512"> product </ci>
</bvar>
<bvar>
<ci definitionURL="http://biomodels.net/SBO/#SBO:0000521"> Inhibitor </ci>
</bvar>
<bvar>
<ci definitionURL="http://biomodels.net/SBO/#SBO:0000322"> Kms </ci>
</bvar>
<bvar>
<ci definitionURL="http://biomodels.net/SBO/#SBO:0000323"> Kmp </ci>
</bvar>
<bvar>
<ci definitionURL="http://biomodels.net/SBO/#SBO:0000324"> Vf </ci>
</bvar>
<bvar>
<ci definitionURL="http://biomodels.net/SBO/#SBO:0000325"> Vr </ci>
</bvar>
<bvar>
<ci definitionURL="http://biomodels.net/SBO/#SBO:0000261"> Ki </ci>
</bvar>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<ci> Vf </ci>
<ci> substrate </ci>
</apply>
<ci> Kms </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> Vr </ci>
<ci> product </ci>
</apply>
<ci> Kmp </ci>
</apply>
</apply>
<apply>
<times/>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> substrate </ci>
<ci> Kms </ci>
</apply>
<apply>
<divide/>
<ci> product </ci>
<ci> Kmp </ci>
</apply>
</apply>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> Inhibitor </ci>
<ci> Ki </ci>
</apply>
</apply>
</apply>
</apply>
</lambda>
</semantics>
</mathml:math></rdfs:seeAlso>
<rdfs:comment>Reversible inhibition of a unireactant enzyme by one inhibitor that can bind to the enzyme-substrate complex and to the free enzyme with the same equilibrium constant. The inhibitor is noncompetitive with the substrate.
</rdfs:comment>
<rdfs:label>enzymatic rate law for simple reversible non-competitive inhibition of unireactant enzymes</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000563">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000562"/>
</rdfs:subClassOf>
<rdfs:seeAlso rdf:parseType="Literal"><mathml:math>
<semantics definitionURL="http://biomodels.net/SBO/#SBO:0000062">
<lambda>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000036">k</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000509">R</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000524">A</ci></bvar>
<apply>
<times/>
<ci>k</ci>
<ci>R</ci>
<ci>A</ci>
</apply>
</lambda>
</semantics>
</mathml:math> </rdfs:seeAlso>
<rdfs:comment>Reaction scheme where the products are created from a reactant and the change of a product quantity is proportional to the product of the reactant and the stimulator activities. The reaction scheme does not include any reverse process that creates the reactant from the products. The change of a product quantity is proportional to the quantity of the reactant and the stimulator. It is to be used in a reaction modelled using a continuous framework.</rdfs:comment>
<rdfs:label>mass action like rate law for second order irreversible reactions, one reactant, one essential stimulator, continuous scheme</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000321">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000025"/>
</rdfs:subClassOf>
<rdfs:comment>Synonym: kcats </rdfs:comment>
<rdfs:label>substrate catalytic rate constant</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000333">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000049"/>
</rdfs:subClassOf>
<rdfs:seeAlso rdf:parseType="Literal"><mathml:math>
<semantics definitionURL="http://biomodels.net/SBO/#SBO:0000062">
<lambda>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000332">l</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000509">R</ci></bvar>
<apply>
<divide/>
<ci>R</ci>
<ci>l</ci>
</apply>
</lambda>
</semantics>
</mathml:math></rdfs:seeAlso>
<rdfs:comment>Monotonic decrease of a quantity proportionally to its value.</rdfs:comment>
<rdfs:label>monoexponential decay rate law</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000454">
<rdfs:subClassOf rdf:resource="SBO_0000430"/>
<rdfs:seeAlso rdf:parseType="Literal"> <mathml:math>
<semantics definitionURL="http://biomodels.net/SBO/#SBO:0000062">
<lambda>
<bvar>
<ci definitionURL="http://biomodels.net/SBO/#SBO:0000515"> substrate </ci>
</bvar>
<bvar>
<ci definitionURL="http://biomodels.net/SBO/#SBO:0000512"> product </ci>
</bvar>
<bvar>
<ci definitionURL="http://biomodels.net/SBO/#SBO:0000322"> Kms </ci>
</bvar>
<bvar>
<ci definitionURL="http://biomodels.net/SBO/#SBO:0000323"> Kmp </ci>
</bvar>
<bvar>
<ci definitionURL="http://biomodels.net/SBO/#SBO:0000324"> Vf </ci>
</bvar>
<bvar>
<ci definitionURL="http://biomodels.net/SBO/#SBO:0000325"> Vr </ci>
</bvar>
<bvar>
<ci definitionURL="http://biomodels.net/SBO/#SBO:0000261"> Ki </ci>
</bvar>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<ci> Vf </ci>
<ci> substrate </ci>
</apply>
<ci> Kms </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> Vr </ci>
<ci> product </ci>
</apply>
<ci> Kmp </ci>
</apply>
</apply>
<apply>
<plus/>
<cn> 1 </cn>
<apply>
<divide/>
<ci> substrate </ci>
<ci> Kms </ci>
</apply>
<apply>
<divide/>
<ci> product </ci>
<ci> Kmp </ci>
</apply>
<apply>
<power/>
<apply>
<divide/>
<ci> substrate </ci>
<ci> Ki </ci>
</apply>
<cn> 2 </cn>
</apply>
</apply>
</apply>
</lambda>
</semantics>
</mathml:math></rdfs:seeAlso>
<rdfs:comment>Enzymatic rate law where the substrate for an enzyme also acts as a reversible inhibitor. This may entail a second (non-active) binding site for the enzyme. The inhibition constant is then the dissociation constant for the substrate from this second site.</rdfs:comment>
<rdfs:label>enzymatic rate law for reversible substrate inhibition</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000103">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000102"/>
</rdfs:subClassOf>
<rdfs:seeAlso rdf:parseType="Literal"><mathml:math>
<semantics definitionURL="http://biomodels.net/SBO/#SBO:0000062">
<lambda>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000036">kf</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000039">kr</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000509">R1</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000509">R2</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000512">P</ci></bvar>
<apply>
<minus/>
<apply>
<times/>
<ci>kf</ci>
<ci>R1</ci>
<ci>R2</ci>
</apply>
<apply>
<times/>
<ci>kr</ci>
<ci>P</ci>
<ci>P</ci>
</apply>
</apply>
</lambda>
</semantics>
</mathml:math></rdfs:seeAlso>
<rdfs:comment>Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of two reactant quantities. The rate of the reverse process is proportional to the square of one product quantity. It is to be used in a reaction modelled using a continuous framework.</rdfs:comment>
<rdfs:label>mass action rate law for second order forward, second order reverse, reversible reactions, two reactants, one product, continuous scheme</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000575">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000573"/>
</rdfs:subClassOf>
<rdfs:comment>The enthalpy change observed in a constituent of a thermodynamic system
when one mole of substance reacts completely, under standard conditions (1
bar). The standard unit of measure is kJ/mol.
Symbol: DeltaHr0, DeltarH0</rdfs:comment>
<rdfs:label>standard enthalpy of reaction</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000224">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000210"/>
</rdfs:subClassOf>
<rdfs:comment>Covalent linkage to the protein ubiquitin. </rdfs:comment>
<rdfs:label>ubiquitination</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000345">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000255"/>
</rdfs:subClassOf>
<rdfs:comment>Fundmental quantity of the measuring system used to sequence events, to compare the durations of events and the intervals between them, and to quantify the motions or the transformation of entities. The SI base unit for time is the SI second. The second is the duration of
9,192,631,770 periods of the radiation corresponding to the transition
between the two hyperfine levels of the ground state of the caesium 133
atom.</rdfs:comment>
<rdfs:label>time</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000466">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000465"/>
</rdfs:subClassOf>
<rdfs:comment>The length of an object is the longest measurable distance between its extremities. </rdfs:comment>
<rdfs:label>length</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000212">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000210"/>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000208"/>
</rdfs:subClassOf>
<rdfs:comment>Addition of a proton (H+) to a chemical entity.</rdfs:comment>
<rdfs:label>protonation</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000006">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000002"/>
</rdfs:subClassOf>
<rdfs:comment>A numerical value that represents the amount of some entity, process or mathematical function of the system.</rdfs:comment>
<rdfs:label>obsolete parameter</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000248">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000245"/>
</rdfs:subClassOf>
<rdfs:comment>Macromolecule whose sequence is not directly encoded in the genome.</rdfs:comment>
<rdfs:label>chemical macromolecule</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000357">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000375"/>
</rdfs:subClassOf>
<rdfs:comment>Biochemical networks can be affected by external influences. Those influences can be well-defined physical perturbations, such as a light pulse, or a change in temperature but also more complex of not well defined phenomena, for instance a biological process, an experimental setup, or a mutation.</rdfs:comment>
<rdfs:label>biological effect of a perturbation</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000478">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000193"/>
</rdfs:subClassOf>
<rdfs:seeAlso rdf:parseType="Literal"><mathml:math>
<lambda>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000027">Km</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000157">x</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000481">n</ci></bvar>
<apply>
<product/>
<bvar><ci> i </ci></bvar>
<lowlimit><cn type="integer"> 1 </cn></lowlimit>
<uplimit><ci> x </ci></uplimit>
<apply>
<power/>
<apply>
<selector/>
<ci type="vector">Km</ci>
<ci> i </ci>
</apply>
<apply>
<selector/>
<ci type="vector">n</ci>
<ci> i </ci>
</apply>
</apply>
</apply>
</lambda>
</mathml:math></rdfs:seeAlso>
<rdfs:comment>The product of the Michaelis constants, to the power of their respective stoichiometric coefficients, for either substrates or products.</rdfs:comment>
<rdfs:label>powered product of Michaelis constant</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000127">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000126"/>
</rdfs:subClassOf>
<rdfs:seeAlso rdf:parseType="Literal"><mathml:math>
<semantics definitionURL="http://biomodels.net/SBO/#SBO:0000062">
<lambda>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000037">kf</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000040">kr</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000509">R1</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000509">R2</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000509">R3</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000512">P</ci></bvar>
<apply>
<minus/>
<apply>
<times/>
<ci>kf</ci>
<ci>R1</ci>
<ci>R2</ci>
<ci>R3</ci>
</apply>
<apply>
<times/>
<ci>kr</ci>
<ci>P</ci>
<ci>P</ci>
<ci>P</ci>
</apply>
</apply>
</lambda>
</semantics>
</mathml:math></rdfs:seeAlso>
<rdfs:comment>Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of three reactant quantities. The rate of the reverse process is proportional to the cube of one product quantity. It is to be used in a reaction modelled using a continuous framework. </rdfs:comment>
<rdfs:label>mass action rate law for third order forward, third order reverse, reversible reactions, three reactants, one product, continuous scheme</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000369">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000354"/>
</rdfs:subClassOf>
<rdfs:comment>Region of a gene that is involved in the modulation of the expression of the gene. </rdfs:comment>
<rdfs:label>gene regulatory region</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000115">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000113"/>
</rdfs:subClassOf>
<rdfs:seeAlso rdf:parseType="Literal"><mathml:math>
<semantics definitionURL="http://biomodels.net/SBO/#SBO:0000062">
<lambda>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000037">kf</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000039">kr</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000509">R1</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000509">R2</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000512">P1</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000512">P2</ci></bvar>
<apply>
<minus/>
<apply>
<times/>
<ci>kf</ci>
<ci>R1</ci>
<ci>R1</ci>
<ci>R2</ci>
</apply>
<apply>
<times/>
<ci>kr</ci>
<ci>P1</ci>
<ci>P2</ci>
</apply>
</apply>
</lambda>
</semantics>
</mathml:math></rdfs:seeAlso>
<rdfs:comment>Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant and the square of quantity of the other reactant. The rate of the reverse process is proportional to the product of two product quantities. It is to be used in a reaction modelled using a continuous framework. </rdfs:comment>
<rdfs:label>mass action rate law for third order forward, second order reverse, reversible reactions, two reactants, two products, continuous scheme</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000236">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000000"/>
</rdfs:subClassOf>
<rdfs:comment>Synonym: new synonym </rdfs:comment>
<rdfs:label>physical entity representation</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000139">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000136"/>
</rdfs:subClassOf>
<rdfs:seeAlso rdf:parseType="Literal"><mathml:math>
<semantics definitionURL="http://biomodels.net/SBO/#SBO:0000062">
<lambda>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000037">kf</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000040">kr</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000509">R</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000512">P1</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000512">P2</ci></bvar>
<bvar><ci definitionURL="http://biomodels.net/SBO/#SBO:0000512">P3</ci></bvar>
<apply>
<minus/>
<apply>
<times/>
<ci>kf</ci>
<ci>R</ci>
<ci>R</ci>
<ci>R</ci>
</apply>
<apply>
<times/>
<ci>kr</ci>
<ci>P1</ci>
<ci>P2</ci>
<ci>P3</ci>
</apply>
</apply>
</lambda>
</semantics>
</mathml:math>
</rdfs:seeAlso>
<rdfs:comment>Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the cube of one reactant quantity. The rate of the reverse process is proportional to the product of three product quantities. It is to be used in a reaction modelled using a continuous framework.</rdfs:comment>
<rdfs:label>mass action rate law for third order forward, third order reverse, reversible reactions, one reactant, three products, continuous scheme</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000018">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000009"/>
</rdfs:subClassOf>
<rdfs:comment>Numerical parameter that quantifies the velocity of a chemical reaction involving three reactants.
</rdfs:comment>
<rdfs:label>trimolecular rate constant</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000663">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000545"/>
</rdfs:subClassOf>
<rdfs:comment>Fractional occupancy is a quantitative dynamic property of a system that can be calculated as the fraction of occupancy over capacity.</rdfs:comment>
<rdfs:label>fractional occupancy</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000651">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000375"/>
</rdfs:subClassOf>
<rdfs:comment>A sequential series of actions, motions, or occurrences, such as chemical reactions, where a reversal of states that bring the system back to its original state in a characteristic manner does not occur.</rdfs:comment>
<rdfs:label>irreversible process</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000530">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000527"/>
</rdfs:subClassOf>
<rdfs:comment>The simultaneous binding modular rate law makes the assumption that substrates and products can be bound simultaneously, and in any combination.</rdfs:comment>
<rdfs:label>simultaneous binding modular rate law</rdfs:label>
</owl:Class>
<owl:Class rdf:about="SBO_0000542">
<rdfs:subClassOf>
<owl:Class rdf:about="SBO_0000002"/>