Skip to content

Commit 9ae2ca1

Browse files
committed
Add README
1 parent f6a7edb commit 9ae2ca1

File tree

1 file changed

+11
-0
lines changed

1 file changed

+11
-0
lines changed

README.md

+11
Original file line numberDiff line numberDiff line change
@@ -0,0 +1,11 @@
1+
# Compiling human protein–protein interactions
2+
3+
This repository collects protein interactions from several resources and creates an integrated catalog of interactions. An interaction refers to when two genes produce protein products that physically interact. Genes are identified using Entrez Gene. See the [Thinklab discussion](http://doi.org/10.15363/thinklab.d85#9) for additional information.
4+
5+
## Execution
6+
7+
[`compile-PPIs.ipynb`](compile-PPIs.ipynb) is a notebook (Python 3.4) which performs the analysis. The combined interaction catalog is exported to [`data/ppi-sources.tsv`](data/ppi-sources.tsv) (each row is a gene–gene–source combination) and [`data/ppi-hetio-ind.tsv`](data/ppi-hetio-ind.tsv) (each row is a gene–gene combination, these interactions are used in the [rephetio](http://doi.org/10.15363/thinklab.4) hetnet).
8+
9+
## License
10+
11+
All original content in this repository is licensed under [CC0 1.0](https://creativecommons.org/publicdomain/zero/1.0/ "CC0 1.0 Universal: Public Domain Dedication"). `hetio-dag` data is licensed as [CC BY 4.0](https://creativecommons.org/licenses/by/4.0/). Incomplete Interactome data is used [with permission](http://doi.org/10.15363/thinklab.d111#3). Please contact the [Human Interactome Database](http://interactome.dfci.harvard.edu/H_sapiens/) regarding the licensing status of their data.

0 commit comments

Comments
 (0)