diff --git a/src/main/java/org/cbioportal/application/rest/vcolumnstore/ColumnStoreStudyController.java b/src/main/java/org/cbioportal/application/rest/vcolumnstore/ColumnStoreStudyController.java
index 2f5a15cb0d1..c8bcb5c28b6 100644
--- a/src/main/java/org/cbioportal/application/rest/vcolumnstore/ColumnStoreStudyController.java
+++ b/src/main/java/org/cbioportal/application/rest/vcolumnstore/ColumnStoreStudyController.java
@@ -9,6 +9,7 @@
 import org.cbioportal.legacy.web.parameter.sort.StudySortBy;
 import org.cbioportal.shared.SortAndSearchCriteria;
 import org.cbioportal.shared.enums.ProjectionType;
+import org.springframework.context.annotation.Profile;
 import org.springframework.http.HttpStatus;
 import org.springframework.http.MediaType;
 import org.springframework.http.ResponseEntity;
@@ -35,6 +36,7 @@
  */
 @RestController
 @RequestMapping("/api/column-store")
+@Profile("clickhouse")
 public class ColumnStoreStudyController {
 
     private final GetCancerStudyMetadataUseCase getCancerStudyMetadataUseCase;
diff --git a/src/main/java/org/cbioportal/cancerstudy/usecase/GetCancerStudyMetadataUseCase.java b/src/main/java/org/cbioportal/cancerstudy/usecase/GetCancerStudyMetadataUseCase.java
index 049e6c62305..47241038b1e 100644
--- a/src/main/java/org/cbioportal/cancerstudy/usecase/GetCancerStudyMetadataUseCase.java
+++ b/src/main/java/org/cbioportal/cancerstudy/usecase/GetCancerStudyMetadataUseCase.java
@@ -4,6 +4,7 @@
 import org.cbioportal.cancerstudy.repository.CancerStudyRepository;
 import org.cbioportal.shared.SortAndSearchCriteria;
 import org.cbioportal.shared.enums.ProjectionType;
+import org.springframework.context.annotation.Profile;
 import org.springframework.stereotype.Service;
 
 import java.util.Collections;
@@ -42,6 +43,7 @@
  * @see CancerStudyMetadata
  */
 @Service
+@Profile("clickhouse")
 public final class GetCancerStudyMetadataUseCase {
 
     private final CancerStudyRepository studyRepository;
diff --git a/src/main/java/org/cbioportal/infrastructure/repository/clickhouse/cancerstudy/ClickhouseCancerStudyRepository.java b/src/main/java/org/cbioportal/infrastructure/repository/clickhouse/cancerstudy/ClickhouseCancerStudyRepository.java
index e889a6c8715..a523ee1f5f4 100644
--- a/src/main/java/org/cbioportal/infrastructure/repository/clickhouse/cancerstudy/ClickhouseCancerStudyRepository.java
+++ b/src/main/java/org/cbioportal/infrastructure/repository/clickhouse/cancerstudy/ClickhouseCancerStudyRepository.java
@@ -3,6 +3,7 @@
 import org.cbioportal.cancerstudy.CancerStudyMetadata;
 import org.cbioportal.cancerstudy.repository.CancerStudyRepository;
 import org.cbioportal.shared.SortAndSearchCriteria;
+import org.springframework.context.annotation.Profile;
 import org.springframework.stereotype.Repository;
 
 import java.util.List;
@@ -12,6 +13,7 @@
  * This class delegates database queries to {@link ClickhouseCancerStudyMapper}.
  */
 @Repository
+@Profile("clickhouse")
 public class ClickhouseCancerStudyRepository implements CancerStudyRepository {
     
     private final ClickhouseCancerStudyMapper cancerStudyMapper;