diff --git a/end-to-end-test/local/specs/web-tour.spec.js b/end-to-end-test/local/specs/web-tour.spec.js
index 03b42f3abf9..03b2a80d73b 100644
--- a/end-to-end-test/local/specs/web-tour.spec.js
+++ b/end-to-end-test/local/specs/web-tour.spec.js
@@ -523,7 +523,7 @@ describe('Group Comparison Tour', function() {
         !tourModal.$(NEXT_STEP_BTN).isDisplayed();
 
         // There should be a compare button [data-tour="mutated-genes-table-compare-btn"]
-        const compareBtn = $('[data-tour="mutated-genes-table-compare-btn"]');
+        const compareBtn = $('[data-test="mutated-genes-table-compare-btn"]');
         compareBtn.waitForDisplayed();
 
         // Click the compare button, the tour should go to the next step
diff --git a/end-to-end-test/remote/specs/core/studyview.spec.js b/end-to-end-test/remote/specs/core/studyview.spec.js
index 3d41e42caa5..241091acee8 100644
--- a/end-to-end-test/remote/specs/core/studyview.spec.js
+++ b/end-to-end-test/remote/specs/core/studyview.spec.js
@@ -984,6 +984,24 @@ describe('study view treatments table', () => {
         assertScreenShotMatch(res);
     });
 
+    it('compare button appears when selecting multiple rows in sample treatments', async () => {
+        const sampleTreatmentsFirstCheckbox =
+            '[data-test="SAMPLE_TREATMENTS-table"] .ReactVirtualized__Table__row:nth-child(1) input';
+        const sampleTreatmentsSecondCheckbox =
+            '[data-test="SAMPLE_TREATMENTS-table"] .ReactVirtualized__Table__row:nth-child(2) input';
+        const sampleTreatmentsCompareButton = '[data-test="table-compare-btn"]';
+        const url = `${CBIOPORTAL_URL}/study/summary?id=lgg_ucsf_2014`;
+        await goToUrlAndSetLocalStorage(url);
+
+        await (await getElement(sampleTreatmentsFirstCheckbox)).waitForExist();
+        await clickElement(sampleTreatmentsFirstCheckbox);
+        await (await getElement(sampleTreatmentsSecondCheckbox)).waitForExist();
+        await clickElement(sampleTreatmentsSecondCheckbox);
+        assert(
+            await (await getElement(sampleTreatmentsCompareButton)).isExisting()
+        );
+    });
+
     it('can filter a study by patient treatments', async () => {
         const url = `${CBIOPORTAL_URL}/study/summary?id=lgg_ucsf_2014`;
         await goToUrlAndSetLocalStorage(url);
@@ -1004,6 +1022,30 @@ describe('study view treatments table', () => {
         const res = await checkElementWithMouseDisabled('#mainColumn');
         assertScreenShotMatch(res);
     });
+
+    it('compare button appears when selecting multiple rows in patient treatments', async () => {
+        const url = `${CBIOPORTAL_URL}/study/summary?id=lgg_ucsf_2014`;
+        await goToUrlAndSetLocalStorage(url);
+
+        const patientTreatmentsFirstCheckbox =
+            '[data-test="PATIENT_TREATMENTS-table"] .ReactVirtualized__Table__row:nth-child(1) input';
+        const patientTreatmentsSecondCheckbox =
+            '[data-test="PATIENT_TREATMENTS-table"] .ReactVirtualized__Table__row:nth-child(2) input';
+        const patientTreatmentsCompareButton =
+            '[data-test="table-compare-btn"]';
+
+        await (await getElement(patientTreatmentsFirstCheckbox)).waitForExist();
+        await clickElement(patientTreatmentsFirstCheckbox);
+        await (
+            await getElement(patientTreatmentsSecondCheckbox)
+        ).waitForExist();
+        await clickElement(patientTreatmentsSecondCheckbox);
+        assert(
+            await (
+                await getElement(patientTreatmentsCompareButton)
+            ).isExisting()
+        );
+    });
 });
 
 describe('study view mutations table', () => {
diff --git a/src/pages/studyView/charts/ChartContainer.tsx b/src/pages/studyView/charts/ChartContainer.tsx
index 5fbe49a8252..555dd30c89e 100644
--- a/src/pages/studyView/charts/ChartContainer.tsx
+++ b/src/pages/studyView/charts/ChartContainer.tsx
@@ -494,6 +494,7 @@ export class ChartContainer extends React.Component<IChartContainerProps, {}> {
                 content: (
                     <div
                         data-tour="mutated-genes-table-compare-btn"
+                        data-test="table-compare-btn"
                         style={{ display: 'flex', alignItems: 'center' }}
                     >
                         <ComparisonVsIcon