diff --git a/.binder/README.md b/.binder/README.md
new file mode 100644
index 0000000000..3ff2958774
--- /dev/null
+++ b/.binder/README.md
@@ -0,0 +1,5 @@
+# .binder/
+
+Configuration files for [binder](https://mybinder.org/) / repo2docker.
+
+Doc: https://mybinder.readthedocs.io/en/latest/using/config_files.html
diff --git a/.binder/apt.txt b/.binder/apt.txt
new file mode 100644
index 0000000000..4fce5fecdc
--- /dev/null
+++ b/.binder/apt.txt
@@ -0,0 +1,5 @@
+clang
+libatlas-base-dev
+libboost-serialization-dev
+libhdf5-serial-dev
+swig
diff --git a/.binder/postBuild b/.binder/postBuild
new file mode 100755
index 0000000000..248a9eab4b
--- /dev/null
+++ b/.binder/postBuild
@@ -0,0 +1,6 @@
+#!/bin/bash
+set -eou pipefail
+
+pip install -e python/sdist[petab,pysb]
+
+scripts/buildBNGL.sh
diff --git a/.binder/runtime.txt b/.binder/runtime.txt
new file mode 100644
index 0000000000..55090899d0
--- /dev/null
+++ b/.binder/runtime.txt
@@ -0,0 +1 @@
+python-3.10
diff --git a/.binder/start b/.binder/start
new file mode 100755
index 0000000000..fd8bf31a7e
--- /dev/null
+++ b/.binder/start
@@ -0,0 +1,6 @@
+#!/bin/bash
+set -eou pipefail
+
+export BNGPATH="$(pwd)/ThirdParty/BioNetGen-2.7.0"
+
+exec "$@"